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KMID : 1036920190240010068
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Annals of Pediatric Endocrinology & Metabolism
2019 Volume.24 No. 1 p.68 ~ p.70
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A case of immune-mediated type 1 diabetes mellitus due to congenital rubella ınfection
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Korkmaz Huseyin Anil
Ermis Cagatay
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Abstract
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Congenital rubella infection is a transplacental infection that can cause intrauterine growth retardation, cataracts, patent ductus arteriosus, hearing loss, microcephaly, thrombocytopenia, and severe fetal injury. It has been shown that type 1 diabetes mellitus develops in 12%?20% of patients with congenital rubella infection, and disorders in the oral glucose tolerance test is observed in 40% of patients. No biochemical or serological markers exist which could indicate that type 1 diabetes was caused by a congenital rubella infection. We report a 13-year-old male patient who was admitted to our hospital with complaints of new-onset polyuria, polydipsia, urination, and weight loss. In addition, he was found to have neurosensory hearing loss, patent ductus arteriosus, and microcephaly. Immunemediated type 1 diabetes mellitus was considered due to the fact that the autoantibodies of diabetes mellitus were positive.
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KEYWORD
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Rubella, Diabetes, Hearing loss
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